MOTION INTEGRITY ARCHITECTUREField evidence · PleniDose
The screens where KineticON was born.
PleniDose is the precision cartridge-filling gantry Bogdan Dicoias designed and built at Panacea Bio Chem. Its control software is where every KineticON idea met a real machine first: a controller link that can drop, a frame that has to be trusted, a brake with an order, and a run that must refuse to start until it has earned it.
About these screenshots. Captured on 17 September 2026 from the PleniDose software running on its developer simulation backend — the same pages and the same code the operator uses on the bench, with no hardware attached. That is why every position reads 0.00, the KineticON™ link reads CLOSED and so many pages say NOT READY. The refusals are the point.
15 screens, one machine
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SCREEN 01 / 15
One application, one machine, two production modes
The PleniDose home screen. Lyoprester handles dual-chamber cartridges (peptidic liquid and P-EARLs aliquoting, middle- and top-plunger pushing); Liquiprester handles liquid cartridges (aliquoting and cartridge closure). The status bar never leaves the top of the screen: simulation badge, the KineticON™ controller link, pump state, X / Y / Z position in millimetres, frame trust and STOP.
KineticON formalises this in The platform →
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SCREEN 02 / 15
Machine Status: readiness is a list of reasons, not a green light
Live status, controller link and frame, the Z brake and the crimper, and one readiness list per workflow. Each missing item says why it is missing and carries a button to the page that fixes it; each commissioned item keeps its value — brake release delay 900 ms, coil release budget 240 s.
KineticON formalises this in Motion integrity →
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SCREEN 03 / 15
Commission the holder: three captures, one diagonal proof
The first row is taught at filling depth and one travel Z serves every row. The machine then predicts the far-left corner from the taught row and the measured plate pitch, and the operator descends there to confirm. The deviation report compares CAD with what was taught — here a taught row pitch of 14.112 mm against a 13.0 mm plate. The screen's own rule: big numbers mean the plate sits crooked; re-seat it and re-teach, never force it.
KineticON formalises this in Machine intelligence →
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SCREEN 04 / 15
Prepare the run: a dose plan at a calibrated speed
Two group volumes — left pump for cannulas 1–4, right pump for 5–8 — with submerge wait, tip-track rise, anti-drip pull-back and a single- or two-speed finish. A speed that has not been calibrated keeps the run NOT READY, and the page shows how far the measurement has got: 0 of 3 points at 30 rpm.
KineticON formalises this in ProcessSync →
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SCREEN 05 / 15
Production: the holder map is the run
The 16 × 36 holder drawn as the run itself. Every well carries its state — pending, in progress, done, skipped, or uncertain and waiting for a recovery decision — beside live counters and the readiness verdict, here 12 of 21 required items complete.
KineticON formalises this in Motion integrity →
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SCREEN 06 / 15
Aseptic cartridge closure: one cartridge per trigger
The 36 × 16 holder drawn to scale (255 × 510 mm, pitch 16.00 × 14.11 mm): select wells, then crimp, go to, skip or include. The readiness panel blocks the run while the KineticON™ link is closed — motion refused until the link is restored — and asks for re-verification because the last geometry confirmation predates geometry fingerprinting. Every run starts at 1A, the near-right corner, and walks one commissioned snake.
KineticON formalises this in Motion integrity →
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SCREEN 07 / 15
Crimper commissioning: geometry taught once, anchored to the frame
The saved first crimp position, row and column pitches, crimp Z, travel Z and park offset. The grid is frame-anchored, so a recalibration shifts it back onto the taught holes, and the page checks that all 576 positions and the park point lie inside the saved travel limits.
KineticON formalises this in Architecture →
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SCREEN 08 / 15
Z brake: a checklist attested in order
Diagnostic release and engage switch only the brake output — no Z motion. The commissioning checklist runs in order: relay click verified; brake releases while commanded on; re-engages while commanded off; a STOP or abort returns the brake to locked; then a tiny braked Z jog, which unlocks only after the first four are ticked.
KineticON formalises this in QuietHold →
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SCREEN 09 / 15
X axis: commanded is not measured
Low-speed commissioning jog and a checklist from driver fitted, supply on and no alarm through microstep setting, limit sensors and direction, to commanded == measured millimetres and a return to origin. The page states it plainly: the controller readout is commanded position, not an encoder — measure the physical travel with a ruler.
KineticON formalises this in Motion integrity →
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SCREEN 10 / 15
Travel limits and frame: trust is re-earned after a power cycle
The frame is open-loop, so it is recalibrated after a power cycle and re-referencing is manual only. FULL CLEAR is attested per tool, the lowest Z point is a saved number, and while Z is below travel height manual X / Y jogs are held to ±2 mm around the descent point.
KineticON formalises this in FrameProof →
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SCREEN 11 / 15
Holders: one record per tool, fingerprinted
Rods head, cannula head and crimper head each keep an identity, a revision, an operator-attested mount confirmation and their taught heights. Any change re-fingerprints the record, and the witnessed dry run has to be earned again.
KineticON formalises this in Machine manifest →
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SCREEN 12 / 15
Reservoir: a volume counted down from a switch
The low-mark level switch starts the count: from the moment it trips, every metered dispense, prime and plumbing loss is subtracted from the volume left. The books can be reconciled against a measured level, and learning resets when the plumbing changes.
KineticON formalises this in Architecture →
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SCREEN 13 / 15
Pump Service: the bench toolkit
Two dispense pumps with four-channel heads and four aspiration pumps split across all eight cannulas, with dispense, aspirate, smart prime, learned prime and a clean cycle that floods, retracts and empties the plumbing. The banner shows that in simulation nothing is sent to the pumps.
KineticON formalises this in Simulation first →
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SCREEN 14 / 15
Commissioning snapshots: every setting, every coordinate, hashed
One folder per snapshot: exact copies of the configuration, the row-fill profile, the crimper holder record, position memory, the reservoir books and recipes, a sha256 manifest and a readable listing of every value — nothing typed by hand. DIFFERENCES compares the live files with a snapshot; a restore is a closed-program action, taken on purpose.
KineticON formalises this in Machine manifest →
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SCREEN 15 / 15
Lyoprester Session A: nine reasons not to start
Four-cartridge liquid scheduling with eight-wide rod pressing. Before a job can start, every Z height must be taught and physical execution must be commissioned; on the simulation backend the page refuses and lists all nine reasons, each with the page that resolves it.
KineticON formalises this in ControlGraph →
Frequently asked
Frequently asked questions
What is PleniDose?
How is PleniDose related to KineticON?
Were these screenshots taken on the real machine?
Why do so many screens say NOT READY?
Current literature
Trending in the field
Recent literature where precise, provable machine motion meets biology and the laboratory — retrieved from PubMed, 17 September 2026.
- Automated Biomedical Research Laboratories: Development, Current State, and a Roadmap for Adaptation into Shared Research Resources — J Biomol Tech, 2026
- Automated implementation of the SwabSeq COVID-19 diagnostic assay on the opentrons flex liquid-handling robot — Diagn Microbiol Infect Dis, 2026 Nov
- Cell-free systems as complementary Test layers for protein engineering in biofoundry workflows — Curr Opin Biotechnol, 2026 Sep 15
- Automated carousel-based electrochemical sensing toward microbiological and oncological settings — Anal Chim Acta, 2026 Sep 22
- Rapid and robust laser-frequency auto-locking using Bayesian-optimization and discrete-wavelet-transformation algorithms — Rev Sci Instrum, 2026 Sep 1
This week in the field
11 – 17 September 2026
Newest PubMed records in robotic manipulation, automated laboratories and precision control — refreshed weekly. Listing only; inclusion is not endorsement.
- A versatile dexterous robotic wrist: lightweight, modular, and pose-adaptive — Bioinspir Biomim, 2026 Sep 15
- Cell-free systems as complementary Test layers for protein engineering in biofoundry workflows — Curr Opin Biotechnol, 2026 Sep 15
- Bibliometric and knowledge-map analysis of research on robot-assisted vascular interventional surgery (2015-2025) — J Robot Surg, 2026 Sep 12
